Km value is defined as?
Substrate concentration at Vmax/2
Km of an enzyme?
Substrate concentration at half maximal velocity
Low Km means?
High affinity
In competitive inhibition?
Vmax unchanged
Competitive inhibition?
Increased Km, Vmax remain same
Km Changes, Vmax is same?
Competitive Enzyme Inhibition
Competitive inhibition?
Reversible non competitive inhibition?
Lower Vmax, Km not affected
Non competitive inhibitor?
Decrease Vmax
Example for non competitive enzyme
inhibition?
Cycloxygenase by aspirin
