Pyrimidine Metabolism – Informational Macromolecules – Biochemistry

Involved in formation of d-TMP from d-UMP?
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N5, N10- methylene tetrahydrofolate

UV light damage to DNA leads to?
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Formation of pyrimidine dimmers

5-methyl adenosine mutation of DNA leads to?
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Deamination to thymidine, DNA repair

Carbomyl Phosphate synthase I found in?
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Mitochondria

Carbomyl phosphate synthase II is found in?
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Cytosol

Nitrogen donor in carbomyl phosphate synthase I?
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Nitrogen donor in carbomyl phosphate synthase II?
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Glutamine

Orotic aciduria is associated with deficiency of?
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Uridine 5 monophosphate synthase

NOT true about pyrimidine metabolism?
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Reye syndrome decrease cytosolic carbomyl phosphate

Damage caused to biological system by UV radiation I by?
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Formation of thymidine dimmers
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